Coupling reaction using transition metal Pd as catalyst has been very efficient in formulating C-C bond

thus Pd catalyzed C-C coupling reaction has been under spotlight of scientist s' attention for years and series of derivative reactions were thence developed

among which Pd catalyzed Solid-phase organic reactions suck as Heck reaction 、Negishi reaction 、Suzuki coupling and Stille coupling

with their accessible reaction conditions

high tolerance of diverse functional groups

low steric hindrance

excellent chemical selectivity

mild toxicity

side products friendly and removable

efficient in yields

have always been the researching focus of catalytic chemistry and solid phase combinatory chemistry .With reference to different classification standards and our own research work

this article reviews the researching progresses of Pd catalized Cross-coupling reactions used in solid phase organic synthesis reactions

such as Heck/Negishi/Suzuki and Stille reaction .