Polyphosphoesters(PPEs)have many repeating phosphoester linkages in their backbone

which allow the introduction of various functional groups. PPEs-based materials have drawn large attentions in potential applications

especially in biomedical materials

due to their favorable biodegradability

biocompatibility

as well as facile functionalization. In this review

we focused on the recent progress of the synthesis of PPEs. The biomedical applications and future developments of PPEs were further discussed based on the previous concept.