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1.哈尔滨工业大学化工学院,哈尔滨 150001
2.威海洁瑞医用制品有限公司,威海 264209
*贺金梅,副教授,主要从事生物医用高分子及聚合物复合材料研究;E-mail:hejinmei@hit.edu.cn.
纸质出版日期:2016-02-20,
收稿日期:2015-04-08,
修回日期:2015-07-22,
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李纪伟, 贺金梅, 尉枫, 黄玉东, 陈晓通. 壳聚糖基防粘连材料的构建及应用进展[J]. 高分子通报, 2016,29(2):86-93.
Ji-wei LI, Jin-mei HE, Feng WEI, YU-dong HUANG, Xiao-tong CHEN. Progress in Preparation and Application of Chitosan-Based Anti-Adhesion Materials[J]. Polymer Bulletin, 2016,29(2):86-93.
李纪伟, 贺金梅, 尉枫, 黄玉东, 陈晓通. 壳聚糖基防粘连材料的构建及应用进展[J]. 高分子通报, 2016,29(2):86-93. DOI: 10.14028/j.cnki.1003-3726.2016.02.010.
Ji-wei LI, Jin-mei HE, Feng WEI, YU-dong HUANG, Xiao-tong CHEN. Progress in Preparation and Application of Chitosan-Based Anti-Adhesion Materials[J]. Polymer Bulletin, 2016,29(2):86-93. DOI: 10.14028/j.cnki.1003-3726.2016.02.010.
术后粘连是影响手术效果甚至手术成败的关键问题之一
因此防止手术后粘连是一个亟待解决的问题。目前
人们已经开发出了多种防粘连材料。壳聚糖由于具有无毒性、无刺激性、无免疫抗原性、无热源性、不溶血、无致突变反应等优异性能
而被广泛用于包括防粘连材料在内的各种生物材料领域。本文结合本课题组在防粘连材料领域的研究
对各种类型壳聚糖基防粘连材料的研究现状及存在问题进行了综述
以期能够为设计和开发新型壳聚糖基防粘连材料提供重要参考。
Postoperative adhesion is one of the key problems which have an influence on the surgical effect. To solve this problem
many anti-adhesion materials have been developed. Chitosan has non-toxic
no stimulation
no immunogenicity
no heat
no hemolysis
no mutagenic response as well as many other excellent properties. For these reasons
chitosan has been widely used in a variety of biological materials
including anti-adhesion materials. In this paper
the progress and problems of chitosan-based anti-adhesion materials were discussed
which may contribute us to effectively design and develop new types of chitosan-based anti-adhesion materials.
壳聚糖溶液膜凝胶防粘连
ChitosanSolutionFilmGelAnti-adhesion
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