Thermosensitive materials can respond to the change of temperature

which is a research focus of stimuliresponsive materials. As a kind of biodegradable polyester with good biocompatibility

poly(lacic acid) (PLA) is widely used in biomedical materials

but its poor hydrophilicity and lack of reactive functional groups in the main chain limit its further application in many areas such as drug control release. By means of functional modification

PLA can be endowed with thermosensitivity

and the obtained thermosensitive PLA-based material can have the excellent properties of both types of materials. At present

the preparation of thermosensitive PLA materials is mostly based on the ring-opening polymerization

combining with other synthesis strategies such as reversible addition-fragmentation chain transfer polymerization

living cationic polymerization and click chemistry. In this paper

the preparation and application of thermosensitive PLA materials in recent years are reviewed according to the classification of the polymers involved in the modification. Development of multi-responsive polymers based on thermosensitive PLA materials and the simplification of preparation methods of related materials will be important.