PLLA/CA honeycomb composite porous membranes were prepared via Breath Figure method under certain humidity and temperature conditions with PLLA and CA as film materials. The effects of factors

such as solvent

relative humidity

polymer concentration

the ratio of polymer

and temperature

on the pore patterns and sizes were investigated. The results show that the pore size of PLLA/CA membranes increases from 1.67±1.34 μm to 5.01±1.34 μm with increasing relative humidity from 43% to 91%. The relationship of pore size and the relative humidity is presented first order liner relationship. Moreover

the slope of straight line is 0.068

which indicates that for every 1% in relative humidity

the pore size increases by 0.068 in this system. When the polymer concentration increases from 1 wt% to 6 wt%

the pore size of honeycomb increases first and then decreases. When the temperature is in the range of 10~50 ℃

the ambient temperature has no significant effect on the pore morphology and size. The water contact angle of pure PLLA honeycomb membrane is 128.1°±2.4°. With the increase of CA content

the water contact angle of porous membrane decreases. When PLLA/CA=5∶5

the water contact angle was 50.2°±1.4°

indicating that a certain amount of CA was added into the system

the hydrophilicity of the porous membrane was improved

which was conducive to the adhesion

migration

reproduction and growth of cells on its surface.