First-generation biomedical materials were biocompatible and bioinert materials.Second-generation biomaterials were designed to be either resorbable or bioactive.Third-generation biomaterials are combining these two properties.These new generation biomaterials are designed as the extracellular matrix to activate genes and elicit the specific interactions with cell
and thereby to direct cell proliferation
differentiation
organization
and last to repair or regenerate the living tissues and organs.
关键词
第三代生物医用材料组织工程细胞和基因活化细胞外基质生物活性
Keywords
Third-generation biomedical materialsTissue engineeringCell and gene-activationExtracellular matrixBioactivity